Amitriptyline can cause side effects on their own, so I took these for 2 weeks starting at 10mg on week 1 and 20mg on week 2. The only reason you were probably told not to take Amitriptyline with Tramadol is side-effects. I have to take them throughout the day at 6 intervals. I suffer from Generalized Dystonia, Functional Episodes and Epilepsy and have to take 25 tablets a day, only one of which is used to counteract side-effects from another tablet. I have tried taking 50mg of Tramadol but I cannot handle the pain. I did not know this and felt nausea the first time I took one, the other thing is to try and keep the dosage as low as possible, I take 100mg a day, as long as I can stand the pain level and get some sleep I am fine. There is a ratio of 10:1 that Tramadol will increase side-effects from other medication, which is why you should never take them together with any other medication. I have to take numerous medication a day, but I have to Tramadol 30 minutes either side of any other medication, the reason for this is because of the side-effects Tramadol may cause, most of them are down to what other medications you already take. Now, what may seem strange is that I am now taking Amitriptyline and Tramadol even though I suffer from Epilepsy, both of these medications can bring on Epileptic Seizures.
After 2 weeks the Tramadol was upped to 50mg in the morning and 50mg at night, this was to ease the pain I am constantly in from nerve and muscle spasms. Then I was put on 50mg of Tramadol as well at night's, it did take awhile before the effects to actually 'kick in'. I was basically watching hours tick by, which seemed to really drag. My Doctor prescribed 20mg of Amitriptyline to be taken at night, for nerve condition pain, which was keeping me awake at nights.